Article
Interaction Between Human Skeletal and Mesenchymal Stem Cells Under Physioxia Enhances Cartilage Organoid Formation: A Phenotypic, Molecular, and Functional Characterization
2025-08-21
Abstract excerpt
Articular cartilage regeneration remains a major challenge due to its limited self-repair capacity. Bone marrow-derived skeletal stem cells (SSCs) and mesenchymal stem cells (MSCs) are promising candidates for cartilage engineering, though they differ in their chondrogenic potential. This study explored whether co-culturing SSCs and MSCs in three-dimensional (3D) organoid systems under cartilage physioxia (5% O₂)...
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Identifiers and source
- Literature Corpus work
- 8e30a2dd-7318-50d6-826e-ef2d80f8ce92
- DOI
- 10.20944/preprints202508.1549.v1
