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Article

DNA repair gene polymorphisms and benefit from gefitinib in never‐smokers with lung adenocarcinoma

24 Jan 2011

Abstract excerpt

BACKGROUND: The objective of this study was to investigate whether polymorphisms in DNA repair genes affect clinical outcome of never-smokers with lung adenocarcinoma (NSLA). METHOD: Common polymorphisms in the DNA repair genes ribonucleotide reductase M1 (RRM1), excision repair cross-complementation group 1 (ERCC1), and x-ray repair cross-complementing group 1 (XRCC1) were genotyped in DNA samples from 158...

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PMID: 21264830
DOI: 10.1002/cncr.25863

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