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Article

Association between polymorphisms in DNA repair genes and survival of non-smoking female patients with lung adenocarcinoma.

BMC cancer - 15 Dec 2009

Yin Zhihua, Zhou Baosen, He Qincheng, Li Mingchuan, Guan Peng, Li Xuelian, Cui Zeshi, Xue Xiaoxia, Su Meng, Ma Rui, Bai Weijun, Xia Shuyue, Jiang Yanduo, Xu Shun, Lv Yi, Li Xun

Abstract excerpt

BACKGROUND: Excision repair cross-complementing group 1 (ERCC1) and group 2 (ERCC2), and X-ray repair cross-complementing group 1 (XRCC1) proteins play important roles in the repair of DNA damage and adducts. Single nucleotide polymorphisms (SNPs) of DNA repair genes are suspected to influence treatment effect and survival of cancer patients. This study aimed to investigate the relationship between polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20003463
DOI: 10.1186/1471-2407-9-439
PMCID: PMC2803496

Genes

ERCC1
XRCC1
ERCC2

Provenance

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