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Article

Dimer-tetramer association equilibria of human adult hemoglobin and its mutants as observed by analytical ultracentrifugation.

Methods (San Diego, Calif.) - 1 May 2011

Arisaka Fumio, Nagai Yukifumi, Nagai Masako

Abstract excerpt

Dimer-tetramer equilibrium of human adult hemoglobin in CO form (COHb A) and its mutants were measured by sedimentation velocity and sedimentation equilibrium. In sedimentation velocity, the association constants were estimated by measuring the concentration dependence of the weight average sedimentation coefficients at pH 6 and 7 and fitting the data to the theoretical binding isotherms with association...

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Identifiers

PMID: 21256216
DOI: 10.1016/j.ymeth.2011.01.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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