Oxygen binding and other physical properties of human hemoglobin made in yeast.

doi:10.1093/protein/5.8.807

Back to search

Article

Oxygen binding and other physical properties of human hemoglobin made in yeast.

Protein engineering - 1 Dec 1992

Adachi K, Konitzer P, Lai C H, Kim J, Surrey S

Abstract excerpt

Wagenbach et al. (1991, BioTechnology, 9, 57-61) have recently developed a system for producing soluble recombinant tetrameric hemoglobin in yeast: hemoglobin begins to appear 4-5 h after induction with galactose, alpha- and beta-globin chains fold in vivo and endogeneously produced heme is incor...

Topics

Allosteric Regulation
Genetic Variation
Hemoglobins
Humans
Hydrogen-Ion Concentration
Oxygen
Protein Conformation
Protein Denaturation
Protein Folding
Recombinant Proteins
Saccharomyces cerevisiae
Transfection

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.