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Aneuploidy in the Human Blastocyst

1 Jan 2011

Abstract excerpt

Studies of human cleavage stage embryos, 3 days after fertilization of the oocyte, have revealed remarkably high levels of chromosome abnormality. In addition to meiotic errors derived from the gametes, principally the oocyte, mitotic errors occurring after fertilization are also common, leading to widespread chromosomal mosaicism. The prevalence of chromosome anomalies in embryos may explain the relatively poor...

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PMID: 21252488
DOI: 10.1159/000323500

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