Article
Characterization of novel and uncharacterized p53 SNPs in the Chinese population--intron 2 SNP co-segregates with the common codon 72 polymorphism.
PloS one - 10 Jan 2011
Phang Beng Hooi, Chua Hui Wan, Li Huihua, Linn Yeh Ching, Sabapathy Kanaga
Abstract excerpt
Multiple single nucleotide polymorphisms (SNPs) have been identified in the tumor suppressor gene p53, though the relevance of many of them is unclear. Some of them are also differentially distributed in various ethnic populations, suggesting selective functionality. We have therefore sequenced all exons and flanking regions of p53 from the Singaporean Chinese population and report here the characterization of...
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