Article
Association of TP53 Codon 72 Arg>Pro Polymorphism with Breast and Lung Cancer Risk in the South Asian Population: A Meta-Analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jun 2020
Jafrin Sarah, Aziz Md Abdul, Anonna Shamima Nasrin, Akter Tahmina, Naznin Nura Ershad, Reza Sharif, Islam Mohammad Safiqul
Abstract excerpt
BACKGROUND: A transversion missense polymorphism of the TP53 tumor suppressor gene at the codon 72 codes proline instead of arginine causes an altered p53 protein expression and has been found to be associated with an elevated risk of various cancer; especially breast and lung cancer. As the previous case-control studies on the South Asian population have shown controversial results, we performed a meta-analysis...
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