Article
Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America - 1 Dec 1990
Eissenberg J C, James T C, Foster-Hartnett D M, Hartnett T, Ngan V, Elgin S C
Abstract excerpt
We report here that a point mutation in the gene which encodes the heterochromatin-specific nonhistone chromosomal protein HP-1 in Drosophila melanogaster is associated with dominant suppression of position-effect variegation. The mutation, a G-to-A transition at the first nucleotide of the last...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Chromobox Protein Homolog 5
- Chromosomal Proteins, Non-Histone
- Cloning, Molecular
- DNA
- Drosophila melanogaster
- Gene Library
- Heterochromatin
- Molecular Sequence Data