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Article

A heat shock-activated cDNA rescues the recessive lethality of mutations in the heterochromatin-associated protein HP1 of Drosophila melanogaster.

Molecular & general genetics : MGG - 1 Sept 1993

Eissenberg J C, Hartnett T

Abstract excerpt

HP1 is a small nonhistone chromosomal protein of Drosophila melanogaster predominantly localized to the pericentric heterochromatin. We have shown previously that mutations in the HP1 coding sequences are associated with dominant suppression of heterochromatic position-effect variegation, and with recessive lethality. When fused to an Hsp70 heat shock gene promoter, the cDNA encoding HP1 supports the heat...

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PMID: 8413181
DOI: 10.1007/BF00280383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A heat shock-activated cDNA rescues the recessive lethality of mutations in the heterochromatin-associated protein HP1 of Drosophila melanogaster.PMID 8413181Read ↗

The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation.Semantic proximity Read ↗

Phosphorylation of heterochromatin protein 1 by casein kinase II is required for efficient heterochromatin binding in Drosophila.Semantic proximity Read ↗

Characterization of sequences associated with position-effect variegation at pericentric sites in Drosophila heterochromatin.Semantic proximity Read ↗

Heterochromatin protein 1 is recruited to various types of DNA damage.Semantic proximity Read ↗

Hip, an HP1-interacting protein, is a haplo- and triplo-suppressor of position effect variegation.Semantic proximity Read ↗

Loss of Hsp70 in Drosophila is pleiotropic, with effects on thermotolerance, recovery from heat shock and neurodegeneration.Semantic proximity Read ↗

Early embryonic heat shock induces long-term epigenetic memory by affecting the transition to zygotic independenceSemantic proximity Read ↗

Heterochromatin protein 1 is required for the normal expression of two heterochromatin genes in Drosophila.Semantic proximity Read ↗

The genomic silencing of position-effect variegation in Drosophila melanogaster: interaction between the heterochromatin-associated proteins Su(var)3-7 and HP1.Semantic proximity Read ↗

<i>Caenorhabditis elegans </i><scp>HSF</scp>‐1 is an essential nuclear protein that forms stress granule‐like structures following heat shockSemantic proximity Read ↗

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.Semantic proximity Read ↗

A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene.Semantic proximity Read ↗

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