Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of adeno-associated virus-2-mediated human BMP-7 gene transfection on the phenotype of nucleus pulposus cells.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2011

Wang Chaofeng, Ruan Di-Ke, Zhang Chao, Wang De-Li, Xin Hongkui, Zhang Yan

Abstract excerpt

Bone morphogenetic protein-7 (BMP-7) was found to stimulate the synthesis of proteoglycans (PGs) and collagen type II. To increase the biological function of the nucleus pulposus (NP) cells, the Ad-hBMP-7 vector was also successfully constructed and transfected NP cells. However, the disadvantage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aggrecans
Share to Bone Morphogenetic Protein 7
Share to Collagen Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type II

Share to Dependovirus

Share to Genetic Therapy

Share to Intervertebral Disc

Share to Proteoglycans

Source

Identifiers

PMID: 21246612
DOI: 10.1002/jor.21310

Genes

BMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21246612-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of adeno-associated virus-2-mediated human BMP-7 gene transfection on the phenotype of nucleus pulposus cells.PMID 21246612Read ↗

Effect of lentivirus-mediated growth and differentiation factor-5 transfection on differentiation of rabbit nucleus pulposus mesenchymal stem cellsSemantic proximity Read ↗

Variations in gene and protein expression in canine chondrodystrophic nucleus pulposus cells following long-term three-dimensional culture.Semantic proximity Read ↗

Gene-Enhanced Tissue EngineeringSemantic proximity Read ↗

Direct delayed human adenoviral BMP-2 or BMP-6 gene therapy for bone and cartilage regeneration in a pony osteochondral modelSemantic proximity Read ↗

Roles of FGF-2 and TGF-beta/FGF-2 on differentiation of human mesenchymal stem cells towards nucleus pulposus-like phenotype.Semantic proximity Read ↗

BMP3 Alone and Together with TGF-β Promote the Differentiation of Human Mesenchymal Stem Cells into a Nucleus Pulposus-Like Phenotype.Semantic proximity Read ↗

Gene therapy for bone formation: In vitro and in vivo osteogenic activity of an adenovirus expressing BMP7Semantic proximity Read ↗

Adeno-associated virus-mediated bone morphogenetic protein-4 gene therapy for in vivo bone formation.Semantic proximity Read ↗

Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein‐7Semantic proximity Read ↗

Comparative analysis in continuous expansion of bovine and human primary nucleus pulposus cells for tissue repair applications.Semantic proximity Read ↗

Effects of nucleus pulposus cell-derived acellular matrix on the differentiation of mesenchymal stem cells.Semantic proximity Read ↗

Comparative Effects of Bone Morphogenetic Proteins and Sox9 Overexpression on Matrix Accumulation by Bovine Anulus Fibrosus CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.