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Article

Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein‐7

19 May 2003

Abstract excerpt

BACKGROUND: Cartilage has a limited capacity to heal. Although chondrocyte transplantation is a useful therapeutic strategy, the repair process can be lengthy. Previously we have shown that over expression of bone morphogenetic protein-7 (BMP-7) in chondrocytes by adenovirus-mediated gene transfer leads to increased matrix synthesis and cartilage-like tissue formation in vitro. In this context we hypothesized...

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PMID: 12798054
DOI: 10.1016/s0736-0266(02)00264-4

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