Article

Effect of lentivirus-mediated growth and differentiation factor-5 transfection on differentiation of rabbit nucleus pulposus mesenchymal stem cells

2020-10-22

Abstract excerpt

<title>Abstract</title> <p>Background：Intervertebral disc degeneration (IDD) is a natural progression of age-related process. Degenerative disc disease (DDD) is a pathologic condition associated with IDD that has been one of the most common causes of chronic low back pain, which can have a severe impact on patients’ quality of life. The purpose of this study is to observe the biological and cytological characteri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 87bed77c-d3ed-51a6-9ca3-73989eddc6dd
DOI: 10.21203/rs.3.rs-40034/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Effect of lentivirus-mediated growth and differentiation factor-5 transfection on differentiation of rabbit nucleus pulposus mesenchymal stem cellsDOI 10.21203/rs.3.rs-40034/v2Read

Current Insights Into the Maintenance of Structure and Function of Intervertebral Disc: A Review of the Regulatory Role of Growth and Differentiation Factor-5Semantic proximity Read

Growth and Differentiation Factor-5 Contributes to the Structural and Functional Maintenance of the Intervertebral DiscSemantic proximity Read

The Role of the Bone Morphogenic Protein Agonist Noggin for Nucleus Pulposus Intervertebral Disc CellsSemantic proximity Read

Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture SystemSemantic proximity Read

Aberrantly expressed long noncoding RNAs in adipose-derived mesenchymal stem cells differentiation to nucleus pulposus-like cellsSemantic proximity Read

Release of active and depot GDF-5 after adenovirus-mediated overexpression stimulates rabbit and human intervertebral disc cellsSemantic proximity Read

[Restoring phenotype of dedifferentiated normal nucleus pulposus cells by resveratrol].Semantic proximity Read

Retinoic acid inhibits the pyroptosis of degenerated nucleus pulposus cells by activating Sirt1-SOD2 signalingSemantic proximity Read

MicroRNA-140-3p alleviates intervertebral disc degeneration via KLF5/N-cadherin/MDM2/Slug axisSemantic proximity Read

1999 Volvo Award Winner in Basic Science StudiesSemantic proximity Read

Gene Therapy Approach for Intervertebral Disc Degeneration: An UpdateSemantic proximity Read

Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine ExosomesSemantic proximity Read