Article
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Hepatology (Baltimore, Md.) - 1 Feb 2011
Suzuki Fumitaka, Suzuki Yoshiyuki, Akuta Norio, Sezaki Hitomi, Hirakawa Miharu, Kawamura Yusuke, Hosaka Tetsuya, Kobayashi Masahiro, Saito Satoshi, Arase Yasuji, Ikeda Kenji, Kobayashi Mariko, Chayama Kazuaki, Kamatani Naoyuki, Nakamura Yusuke, Miyakawa Yuzo, Kumada Hiromitsu
Abstract excerpt
UNLABELLED: Polymorphisms of the inosine triphosphatase (ITPA) gene influence anemia during pegylated interferon (PEG-IFN) and ribavirin (RBV) therapy, but their effects during triple therapy with PEG-IFN, RBV, and telaprevir are not known. Triple therapy for 12 weeks, followed by PEG-IFN and RBV...
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