Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin.

doi:10.3851/IMP1796

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Article

Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin.

Antiviral therapy - 1 Jan 2011

Kurosaki Masayuki, Tanaka Yasuhito, Tanaka Keisuke, Suzuki Yuichiro, Hoshioka Yoshihide, Tamaki Nobuharu, Kato Tomoji, Yasui Yutaka, Hosokawa Takanori, Ueda Ken, Tsuchiya Kaoru, Kuzuya Teiji, Nakanishi Hiroyuki, Itakura Jun, Takahashi Yuka, Asahina Yasuhiro, Matsuura Kentaro, Sugauchi Fuminaka, Enomoto Nobuyuki, Nishida Nao, Tokunaga Katsushi, Mizokami Masashi, Izumi Namiki

Abstract excerpt

BACKGROUND: A genome-wide association study revealed an association between variants of the inosine triphosphatase (ITPA) gene and ribavirin (RBV)-induced anaemia. The aim of this study was to replicate this finding in an independent Japanese cohort and to define a method to allow pretreatment prediction of anaemia in combination with other factors. METHODS: Genotype 1b chronic hepatitis C patients (n=132)...

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Identifiers

PMID: 21817190
DOI: 10.3851/IMP1796

Genes

ITPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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