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Article

Stenotic aortic valves have dysfunctional mechanisms of anti-inflammation: implications for aortic stenosis.

The Journal of thoracic and cardiovascular surgery - 1 Feb 2011

Lee Joon H, Meng Xianzhong, Weyant Michael J, Reece T Brett, Cleveland Joseph C, Fullerton David A

Abstract excerpt

OBJECTIVE: Aortic stenosis is an inflammatory disease, associated with increased tissue levels of interleukin-1 beta. We hypothesized that the antagonist of interleukin-1 beta, interleukin-1 receptor antagonist, is deficient in aortic valves and that its production by aortic valve interstitial ce...

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Source

Identifiers

PMID: 21241861
DOI: 10.1016/j.jtcvs.2010.11.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21241861-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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