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Article

Interleukin-1 Beta induces an inflammatory phenotype in human aortic valve interstitial cells through nuclear factor kappa Beta.

The Annals of thoracic surgery - 1 Jul 2013

Nadlonek Nicole, Lee Joon H, Reece T Brett, Weyant Michael J, Cleveland Joseph C, Meng Xianzhong, Fullerton David A

Abstract excerpt

BACKGROUND: Mechanisms of inflammation have been implicated in the pathogenesis of aortic stenosis. When stimulated, human aortic valve interstitial cells (AVICs) have been shown to become inflammatory cells. Increased levels of interleukin (IL)-1β have been found in the leaflets of stenotic aort...

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Identifiers

PMID: 23735716
DOI: 10.1016/j.athoracsur.2013.04.013
PMCID: PMC3833085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23735716-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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