Article

Memory CD4+ T cells do not induce graft-versus-host disease

2003-07-01

Abstract excerpt

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality in allogeneic stem cell transplantation (alloSCT). Donor T cells that accompany stem cell grafts cause GVHD by attacking recipient tissues; therefore, all patients receive GVHD prophylaxis by depletion of T cells from the allograft or through immunosuppressant drugs. In addition to providing a graft-versusleukemia effect, donor T cel...

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Literature Corpus work: 195a54d3-6b0d-5671-bdcb-3cdf7fd92616
DOI: 10.1172/jci200317601

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