Article
Yeast prions: could they be exaptations? The URE2/[URE3] system in Kluyveromyces lactis.
FEMS yeast research - 1 Feb 2011
Safadi Rim Al, Talarek Nicolas, Jacques Noémie, Aigle Michel
Abstract excerpt
We examined aspects of the URE2/[URE3] prion system in Kluyveromyces lactis, which lies on a different evolutionary branch from Saccharomyces. We first analysed the polymorphism of the prion-forming domain in 38 strains. Considerable differences were found between these two genera, with little variation within K. lactis. We then analysed the regulatory function of Ure2p, using a deletion of URE2. We assessed the...
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