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The [URE3] yeast prion: from genetics to biochemistry.

Biochemistry. Biokhimiia - 1 Dec 1999

Komar A A, Melki R, Cullin C

Abstract excerpt

[URE3] is a non-Mendelian genetic element of the yeast Saccharomyces cerevisiae, an altered prion form of Ure2 protein. We show that recombinant Ure2p is a soluble protein that can assemble in vitro into dimers, tetramers, and octamers or form insoluble fibrils observed for PrP in its filamentous...

Topics

Fungal Proteins
Genes, Fungal
Glutathione Peroxidase
Microscopy, Electron
Models, Biological
Phenotype
Prions
Protein Structure, Quaternary
Protein Structure, Tertiary
Recombinant Fusion Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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PMID: 10648964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10648964-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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