Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

The yeast prion [URE3] can be greatly induced by a functional mutated URE2 allele.

The EMBO journal - 3 Jul 2000

Fernandez-Bellot E, Guillemet E, Cullin C

Abstract excerpt

The non-Mendelian element [URE3] of yeast is considered to be a prion form of the Ure2 protein. The [URE3] phenotype occurs at a frequency of 10(-5) in haploid yeast strains, is reversible, and its frequency is increased by overexpressing the URE2 gene. We created a new mutant of the Ure2 protein...

Topics

Alleles
Base Sequence
DNA Primers
Fungal Proteins
Glutathione Peroxidase
Green Fluorescent Proteins
Luminescent Proteins
Mutagenesis
Prions
Recombinant Fusion Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 10880435
DOI: 10.1093/emboj/19.13.3215
PMCID: PMC313950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10880435-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The yeast prion [URE3] can be greatly induced by a functional mutated URE2 allele.PMID 10880435Read ↗

The [URE3] yeast prion: from genetics to biochemistry.Semantic proximity Read ↗

A promiscuous prion: efficient induction of [URE3] prion formation by heterologous prion domains.Semantic proximity Read ↗

The [URE3] phenotype: evidence for a soluble prion in yeast.Semantic proximity Read ↗

Induction of distinct [URE3] yeast prion strains.Semantic proximity Read ↗

Mutations Outside the Ure2 Amyloid-Forming Region Disrupt [URE3] Prion Propagation and Alter Interactions with Protein Quality Control Factors.Semantic proximity Read ↗

The protein-only theory and the yeast Saccharomyces cerevisiae: the prions and the propagons.Semantic proximity Read ↗

Two prion-inducing regions of Ure2p are nonoverlapping.Semantic proximity Read ↗

In vitro analysis of SpUre2p, a prion-related protein, exemplifies the relationship between amyloid and prion.Semantic proximity Read ↗

[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae.Semantic proximity Read ↗

Hermes Transposon Mutagenesis Shows [URE3] Prion Pathology Prevented by a Ubiquitin-Targeting Protein: Evidence for Carbon/Nitrogen Assimilation Cross Talk and a Second Function for Ure2p in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast prions form infectious amyloid inclusion bodies in bacteriaSemantic proximity Read ↗

Prions of yeast as heritable amyloidoses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.