Article
The HAP2 subunit of yeast CCAAT transcriptional activator contains adjacent domains for subunit association and DNA recognition: model for the HAP2/3/4 complex.
Genes & development - 1 Oct 1990
Olesen J T, Guarente L
Abstract excerpt
Budding yeast HAP2 is required in concert with HAP3 and HAP4 to form a heterotrimeric CCAAT-binding transcriptional activation complex at the UAS2 element of CYC1. Functional homologs of HAP2 and HAP3 have been conserved in HeLa cells where HAP2 activity corresponds to a chromatographic fraction...
Topics
- Amino Acids
- CCAAT-Binding Factor
- Chromosome Deletion
- Chromosome Mapping
- Cloning, Molecular
- Codon
- DNA, Fungal
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Models, Genetic
- Mutagenesis
- Mutation
- Plasmids
- Saccharomyces cerevisiae
- Transcription Factors
- beta-Galactosidase