Article
Characterization of a promoter mutation in the CYP3 gene of Saccharomyces cerevisiae which cancels regulation by Cyp1p (Hap1p) without affecting its binding site.
Molecular & general genetics : MGG - 27 Nov 1996
Lodi T, Petrochilo E, Gaisne M, Verdière J
Abstract excerpt
Cyp1p (Hap1p) activates, among others, the two structural genes, CYC1 and CYP3 (CYC7) which encode isocytochromes c in Saccharomyces cerevisiae. This activation is believed to occur through the binding of the protein to the dissimilar upstream activation sequences (UASs), UAS1 and UAS', present u...
Topics
- Alleles
- Base Sequence
- Binding Sites
- Cytochrome c Group
- Cytochromes c
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Phenotype
- Promoter Regions, Genetic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion
- Trans-Activators
- Transcription Factors