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Article

SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma.

Blood - 17 Mar 2011

Wrench David, Leighton Pamela, Skibola Christine F, Conde Lucia, Cazier Jean-Baptiste, Matthews Janet, Iqbal Sameena, Carlotti Emanuela, Bödör Csaba, Montoto Silvia, Calaminici Maria, Gribben John G, Lister T Andrew, Fitzgibbon Jude

Abstract excerpt

Inherited risk determinants for follicular lymphoma (FL) have recently been described in the immune gene-rich human leukocyte antigen region on chromosome 6p. The known importance of host immune response to FL survival led us to evaluate these germline factors in FL outcome. We confirm the association of single nucleotide polymorphisms rs10484561 (P = 3.5 × 10⁻⁹) and rs6457327 (P = .008) with risk of FL and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic
Share to Chromosomes, Human, Pair 6
Share to HLA Antigens
Share to Lymphoma, Follicular
Share to Polymorphism, Single Nucleotide
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Source

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Identifiers

PMID: 21233317
DOI: 10.1182/blood-2010-10-315382
PMCID: PMC3062316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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