Article
Human leukocyte antigen class I and II alleles and overall survival in diffuse large B-cell lymphoma and follicular lymphoma.
TheScientificWorldJournal - 1 Jan 2011
Lu Yani, Abdou Amr M, Cerhan James R, Morton Lindsay M, Severson Richard K, Davis Scott, Cozen Wendy, Rothman Nathaniel, Bernstein Leslie, Chanock Stephen, Hartge Patricia, Wang Sophia S
Abstract excerpt
Genetic variation in the 6p21 chromosomal region, including human leukocyte antigen (HLA) genes and tumor necrosis factor (TNF), has been linked to both etiology and clinical outcomes of lymphomas. We estimated the effects of HLA class I (A, B, and C), class II DRB1 alleles, and the ancestral haplotype (AH) 8.1 (HLAA*01-B*08-DRB1*03-TNF-308A) on overall survival (OS) among patients with diffuse large B-cell...
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