Article
Association of HLA-DQB1 alleles with risk of follicular lymphoma.
Leukemia & lymphoma - 1 Jan 2011
Akers Nicholas K, Curry John D, Conde Lucia, Bracci Paige M, Smith Martyn T, Skibola Christine F
Abstract excerpt
In a recent genome-wide association study of follicular lymphoma (FL), we identified novel risk alleles on chromosome 6p21.33 that appeared to be part of an extended haplotype including HLA-DRB1*0101, DQA1*0101, and DQB1*0501. To follow up on these findings, we obtained 2-4 digit HLA-DQB1 allelotypes on a subset of 265 cases of FL and 757 controls using a novel assay that applies multiplexed ligation-dependent...
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