Article
14-3-3σ controls corneal epithelium homeostasis and wound healing.
Investigative ophthalmology & visual science - 1 Apr 2011
Lu Qingxian, Xin Ying, Ye Fei, Foulks Gary, Li Qiutang
Abstract excerpt
PURPOSE: To investigate the functional role of 14-3-3σ in regulation of the corneal epithelial proliferation, differentiation, and wound-healing response. METHODS: Corneal phenotypes were investigated in heterozygous repeated epilation (Er) mice carrying mutations in the sfn (14-3-3σ) gene. Immunohistochemistry was used to study the corneal morphogenesis of the Er/Er embryos at embryonic day (E)18.5. Corneal...
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