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Article

Down‐regulation of <i>Pax6</i> is associated with abnormal differentiation of corneal epithelial cells in severe ocular surface diseases

21 Nov 2007

Abstract excerpt

Pax6 is the universal master control gene for eye morphogenesis. Other than retina and lens, Pax6 also expressed in the ocular surface epithelium from early gestation until the postnatal stage, in which little is known about the function of Pax6. In this study, corneal pannus tissues from patients with ocular surface diseases such as Stevens-Johnson syndrome (SJS), chemical burn, aniridia and recurrent pterygium...

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Share to Corneal surgery and disorders
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PMID: 18027901
DOI: 10.1002/path.2256

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