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Article

The cell cycle regulator protein 14-3-3σ is essential for hair follicle integrity and epidermal homeostasis.

The Journal of investigative dermatology - 1 Jun 2012

Hammond Nigel L, Headon Denis J, Dixon Michael J

Abstract excerpt

The 14-3-3σ (Stratifin; Sfn) is a cell cycle regulator intimately involved in the program of epithelial keratinization. 14-3-3σ is unique in that it is expressed primarily in epithelial cells and is frequently silenced in epithelial cancers. Despite its well-documented role as a cell cycle regulator and as a tumor suppressor, the function of 14-3-3σ in the intricate balance of proliferation and differentiation in...

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Identifiers

PMID: 22377760
DOI: 10.1038/jid.2012.27
PMCID: PMC3378636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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