Article
A comprehensive review of genetic association studies.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000
Hirschhorn Joel N, Lohmueller Kirk, Byrne Edward, Hirschhorn Kurt
Abstract excerpt
Most common diseases are complex genetic traits, with multiple genetic and environmental components contributing to susceptibility. It has been proposed that common genetic variants, including single nucleotide polymorphisms (SNPs), influence susceptibility to common disease. This proposal has begun to be tested in numerous studies of association between genetic variation at these common DNA polymorphisms and...
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