Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DARPins: An Efficient Targeting Domain for Lentiviral Vectors

11 Jan 2011

Abstract excerpt

We have recently developed a retargeting system for lentiviral vectors (LVs) that relies on the pseudotyping of LVs with engineered measles virus (MV) glycoproteins (hemagglutinin (H) and fusion protein (F)). Specificity is provided through display of a single-chain antibody (scFv) as targeting domain by fusion to the MV-H protein. As an alternative to scFv, designed ankyrin repeat proteins (DARPins) can be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Virology and Viral Diseases
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21224833
DOI: 10.1038/mt.2010.298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DARPins: An Efficient Targeting Domain for Lentiviral VectorsPMID 21224833Read ↗

Targeted Cell Entry of Lentiviral VectorsSemantic proximity Read ↗

<i>In vivo</i> generation of chimeric antigen receptor T cells using optimally retargeted and functionalized lentiviral vectors with reduced immune clearanceSemantic proximity Read ↗

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System ManufacturingSemantic proximity Read ↗

Off-target-free gene delivery by affinity-purified receptor-targeted viral vectorsSemantic proximity Read ↗

Efficient and Highly Specific Gene Transfer Using Mutated Lentiviral Vectors Redirected with Bispecific Antibodies.Semantic proximity Read ↗

Adapter-Mediated Transduction with Lentiviral Vectors: A Novel Tool for Cell-Type-Specific Gene TransferSemantic proximity Read ↗

Engineered AAV9 as <i>in vivo</i> gene delivery platform for the selective transduction of TME cell subsetsSemantic proximity Read ↗

Lentiviral Vectors Targeted to MHC II Are Effective in ImmunizationSemantic proximity Read ↗

Cell type-specific delivery by modular envelope designSemantic proximity Read ↗

Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IXSemantic proximity Read ↗

CD8-Specific Designed Ankyrin Repeat Proteins Improve Selective Gene Delivery into Human and Primate T LymphocytesSemantic proximity Read ↗

Simultaneous TCR and IL-2 agonism selectively enhances epitope-specific CD8 T cell responses during chronic viral infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.