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Article

Targeted Cell Entry of Lentiviral Vectors

24 Jun 2008

Abstract excerpt

Retargeting of lentiviral vector entry to cell types of interest is a key factor in improving the safety and efficacy of gene transfer. In this study we show that the retargetable envelope glycoproteins of measles virus (MV), namely, the hemagglutinin (H) responsible for receptor recognition and the fusion protein (F), can pseudotype human immunodeficiency virus 1 (HIV-1) vectors when their cytoplasmic tails are...

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PMID: 18578012
DOI: 10.1038/mt.2008.128

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