Genetic susceptibility, HIV infection, and the kidney.

Abstract excerpt

In recent years, the sequencing of mammalian and microbial genomes has provided the opportunity to study how genetic variation in the host and pathogen influence the course of infectious disease. In the case of HIV-1 infection, such studies have led to identification of key viral proteins that determine pathogenicity, immune evasion, or drug resistance. In addition, candidate gene association studies have...

Topics

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• Disease Models, Animal
• DNA, Viral
• Drug Resistance, Viral
• HIV-1
• HIV Infections