Article
Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3.
Proceedings of the National Academy of Sciences of the United States of America - 24 Feb 2004
Gharavi Ali G, Ahmad Tariq, Wong Robert D, Hooshyar Roozbeh, Vaughn Janene, Oller Sarah, Frankel Rachelle Z, Bruggeman Leslie A, D'Agati Vivette D, Klotman Paul E, Lifton Richard P
Abstract excerpt
HIV-1-associated nephropathy (HIVAN) is a major complication of HIV-1 infection with distinct pathologic features. Introduction of the HIV-1 genome into mice results in a renal disease with all of the histologic and clinical hallmarks of HIVAN on the FVB/N genetic background (TgFVB). We assessed the influence of genetic background on the development or progression of HIVAN by making F1 hybrids of TgFVB with five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.