Article
Vibrio vulnificus rtxA1 gene recombination generates toxin variants with altered potency during intestinal infection.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jan 2011
Kwak Jayme S, Jeong Hee-Gon, Satchell Karla J F
Abstract excerpt
Vibrio vulnificus is a food-borne bacterial pathogen associated with 1% of all food-related deaths, predominantly because of consumption of contaminated seafood. The ability of V. vulnificus to cause disease is linked to the production of a large cytotoxin called the "multifunctional-autoprocessing RTX" (MARTX(Vv)) toxin, a factor shown here to be an important virulence factor by the intragastric route of...
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