Article
CTX genetic element encodes a site-specific recombination system and an intestinal colonization factor.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1993
Pearson G D, Woods A, Chiang S L, Mekalanos J J
Abstract excerpt
In Vibrio cholerae, the genes encoding cholera toxin (ctxAB) are located on a segment of DNA (termed the "core" region) that is flanked by two or more copies of a repeated sequence called RS1. Together these DNA units comprise the CTX genetic element. Evidence presented here suggests that RS1 sequences encode a site-specific recombination system, which allows integration of a suicide plasmid carrying RS1 into an...
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