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Article

Identification and characterization of the Vibrio vulnificus rtxA essential for cytotoxicity in vitro and virulence in mice.

Journal of microbiology (Seoul, Korea) - 1 Apr 2007

Lee Jeong Hyun, Kim Myung Won, Kim Byoung Sik, Kim Seung Min, Lee Byung Cheol, Kim Tae Sung, Choi Sang Ho

Abstract excerpt

A mutant exhibiting decreased cytotoxic activity toward INT-407 intestinal epithelial cells and carrying a mutation in the rtx gene cluster that consists of rtxCA and rtxBDE operons was screened from a library of V. vulnificus mutants. The functions of the rtxA gene, assessed by constructing an isogenic mutant and evaluating its phenotypic changes, demonstrated that RtxA is essential for the virulence of V....

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PMID: 17483800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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