Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Presymptomatic risk assessment for chronic non-communicable diseases.

PloS one - 31 Dec 2010

Padhukasahasram Badri, Halperin Eran, Wessel Jennifer, Thomas Daryl J, Silver Elana, Trumbower Heather, Cargill Michele, Stephan Dietrich A

Abstract excerpt

The prevalence of common chronic non-communicable diseases (CNCDs) far overshadows the prevalence of both monogenic and infectious diseases combined. All CNCDs, also called complex genetic diseases, have a heritable genetic component that can be used for pre-symptomatic risk assessment. Common single nucleotide polymorphisms (SNPs) that tag risk haplotypes across the genome currently account for a non-trivial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Chronic Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to Diabetes Mellitus, Type 2

Share to Genetic Diseases, Inborn

Share to Risk Assessment

Share to ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 21217814
DOI: 10.1371/journal.pone.0014338
PMCID: PMC3013091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Presymptomatic risk assessment for chronic non-communicable diseases.PMID 21217814Read ↗

Susceptible Genes and Polymorphisms Associated with Communicable and Noncommunicable DiseasesSemantic proximity Read ↗

Genetic Risk Scores.Semantic proximity Read ↗

Discovery and implications of polygenicity of common diseases.Semantic proximity Read ↗

Clinical use of polygenic risk scores: current status, barriers and future directions.Semantic proximity Read ↗

Poly-Exposure and Poly-Genomic Scores Implicate Prominent Roles of Non-Genetic and Demographic Factors in Four Common Diseases in the UKSemantic proximity Read ↗

A comprehensive investigation of statistical and machine learning approaches for predicting complex human diseases on genomic variants.Semantic proximity Read ↗

From Basic Science to Clinical Application of Polygenic Risk Scores: A Primer.Semantic proximity Read ↗

Improved prediction of complex diseases by common genetic markers: state of the art and further perspectives.Semantic proximity Read ↗

Systematic classification of shared components of genetic risk for common human diseasesSemantic proximity Read ↗

Exploring the genetic architecture of multimorbidity and its impact on long COVID riskSemantic proximity Read ↗

A Scalable Framework to Integrate Social Determinants of Health into Disease Risk Models using Biobank Survey DataSemantic proximity Read ↗

Prediction of individual genetic risk of complex disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.