Article
HIV genetic diversity between plasma and cerebrospinal fluid in patients with HIV encephalitis.
AIDS (London, England) - 24 Sept 2010
Soulié Cathia, Fourati Slim, Lambert-Niclot Sidonie, Tubiana Roland, Canestri Ana, Girard Pierre-Marie, Katlama Christine, Morand-Joubert Laurence, Calvez Vincent, Marcelin Anne-Geneviève
Abstract excerpt
In patients with HIV encephalitis, a low viral diversity between the plasma and cerebrospinal fluid (CSF) HIV-1 viruses was associated with detectable HIV RNA in plasma and a higher level of central nervous system penetration effectiveness (CPE) score, taking into account the genotypic susceptibility score of the current treatment (named balanced score). This result suggests that the CSF viruses were probably...
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