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Article

PAI-1 4G/5G repeat is a target in gastric carcinomas with microsatellite instability.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jun 2011

Palmirotta Raffaele, Guadagni Fiorella, Savonarola Annalisa, Ludovici Giorgia, Nesi Gabriella, Palli Domenico, Falchetti Mario, Ottini Laura

Abstract excerpt

BACKGROUND: The plasminogen activator inhibitor-1 (PAI-1) plays an important role in the pathogenesis of cancer. The 4G/5G promoter polymorphism of PAI-1 is potentially involved in regulating gene transcription. AIMS: To explore the role of the PAI-1 4G/5G repeat as target of microsatellite instability (MSI), 50 gastric carcinomas (GCs), characterized for MSI, were screened. METHODS: PAI-1 4G/5G was analysed by...

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Share to Plasminogen Activator Inhibitor 1
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA, Neoplasm

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Source

Identifiers

PMID: 21216681
DOI: 10.1016/j.dld.2010.12.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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