Article
Genetic instability and CpG methylation in the 5'-flanking region of the PAI-1 gene in Chinese patients with gastric cancer.
Genetics and molecular research : GMR - 29 Aug 2012
Liu J, Li X, Yu N, Yang Y-Q, Li X, Ye Z-Y, Li J-C
Abstract excerpt
We explored a possible correlation of genetic instability and CpG methylation in the 5'-flanking region of the PAI-1 gene with clinicopathologic features of gastric cancer in Chinese patients and looked for molecular markers for diagnosing gastric tumor development. Microsatellite instability and loss of heterozygosity of the PAI-1 gene locus D7S515, D7S471 and pai-1 in 50 specimens of gastric cancer and...
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