Article
4G/5G and A-844G Polymorphisms of Plasminogen Activator Inhibitor-1 Associated with Glioblastoma in Iran--a Case-Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Pooyan Honari, Ahmad Ebrahimi, Azadeh Rakhshan
Abstract excerpt
BACKGROUND: Glioblastoma is a highly aggressive and malignant brain tumor. Risk factors are largely unknown however, although several biomarkers have been identified which may support development, angiogenesis and invasion of tumor cells. One of these biomarkers is PAI-1. 4G/5G and A-844G are two common polymorphisms in the gene promotor of PAI 1 that may be related to high transcription and expression of this...
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