Article
Plasminogen activator inhibitor -1 gene 4G/5G polymorphism in patients with breast cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Eroglu A, Ulu A, Cam R, Akar N
Abstract excerpt
PURPOSE: The plasminogen activator inhibitor-1 (PAI-1) plays an important role in the development of tumor invasion and metastasis. The 4G allele of 4G/5G insertion / deletion polymorphism located in the promoter region 675 bp upstream from the transcription start sequence of PAI-1 gene is responsible for the higher plasma PAI-1 level. The aim of the present study was to evaluate the association between PAI-1...
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