Article
A common variant in the β2-adrenergic receptor and risk of sudden cardiac death.
Heart rhythm - 1 May 2011
Gavin Michael C, Newton-Cheh Christopher, Gaziano John Michael, Cook Nancy R, VanDenburgh Martin, Albert Christine M
Abstract excerpt
BACKGROUND: Homozygosity for a common nonsynonymous single nucleotide polymorphism (Gln27Glu) in the β(2)-adrenergic receptor gene (ADRB2) has been inconsistently associated with sudden cardiac death (SCD) in individual studies of small sample size. OBJECTIVE: The purpose of this study was to examine the association between the Gln27Glu polymorphism and SCD in a large combined sample of SCD cases. METHODS: Nested...
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