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Article

Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context.

Mechanisms of ageing and development - 1 May 2010

Kulminski Alexander M, Culminskaya Irina, Ukraintseva Svetlana V, Arbeev Konstantin G, Land Kenneth C, Yashin Anatoli I

Abstract excerpt

The Gln(27)Glu polymorphism but not the Arg(16)Gly polymorphism of the beta2-adrenergic receptor (ADRB2) gene appears to be associated with a broad range of aging-associated phenotypes, including cancers at different sites, myocardial infarction (MI), intermittent claudication (IC), and overall/healthy longevity in the Framingham Heart Study Offspring cohort. The Gln(27)Gln genotype increases risks of cancer, MI...

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Source

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Identifiers

PMID: 20399803
DOI: 10.1016/j.mad.2010.04.001
PMCID: PMC2895994

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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