Article
Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.
Heart rhythm - 1 Jun 2008
Tseng Zian H, Aouizerat Bradley E, Pawlikowska Ludmila, Vittinghoff Eric, Lin Feng, Whiteman Dean, Poon Annie, Herrington David, Howard Timothy D, Varosy Paul D, Hulley Stephen B, Malloy Mary, Kane John, Kwok Pui-Yan, Olgin Jeffrey E
Abstract excerpt
BACKGROUND: Previous studies suggest that beta-adrenergic receptor (betaAR) single nucleotide polymorphisms (SNPs) are associated with out-of-hospital sudden cardiac death (SCD) and overall mortality, but did not specifically examine risk of ventricular arrhythmias (VA). OBJECTIVE: This study examined the effects of functional SNPs of beta1AR and beta2AR on the risk of VA and SCD in patients with coronary artery...
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