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Article

C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain.

Developmental biology - 15 Mar 2011

Soloviev Alexander, Gallagher Joseph, Marnef Aline, Kuwabara Patricia E

Abstract excerpt

The nematode Caenorhabditis elegans has retained a rudimentary Hedgehog (Hh) signalling pathway; Hh and Smoothened (Smo) homologs are absent, but two highly related Patched gene homologs, ptc-1 and ptc-3, and 24 ptc-related (ptr) genes are present. We previously showed that ptc-1 is essential for germ line cytokinesis. Here, we report that ptc-3 is also an essential gene; the absence of ptc-3 results in a late...

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Identifiers

PMID: 21215260
DOI: 10.1016/j.ydbio.2010.12.035
PMCID: PMC3078328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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