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Article

Contribution of autophagic cell death to p53-dependent cell death in human glioblastoma cell line SF126.

Cancer science - 1 Apr 2011

Sakamoto Yasuhiro, Kato Shunsuke, Takahashi Masahiro, Okada Yoshinari, Yasuda Katsuhiro, Watanabe Gou, Imai Hiroo, Sato Atsuko, Ishioka Chikashi

Abstract excerpt

Apoptosis and autophagic cell death are programmed cell deaths that are involved in cell survival, growth, development and carcinogenesis. p53, the most extensively studied tumor suppressor, regulates apoptosis and autophagy by transactivating its downstream genes. It also stimulates the mitochondrial apoptotic pathway and inhibits autophagy in a transactivation-independent manner. However, the contribution of...

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Identifiers

PMID: 21214676
DOI: 10.1111/j.1349-7006.2011.01857.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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