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Article

Expression and Function of a Large Non‐coding RNA Gene XIST in Human Cancer

6 Jan 2011

Abstract excerpt

BACKGROUND: X inactive-specific transcript (XIST) RNA is involved in X chromosome silencing in female cells and allows X chromosome equilibration with males. X inactive-specific transcript expression has been found to be dysregulated in a variety of human cancers when compared to normal cells; meanwhile, the inactivated X chromosome has been noted to be conspicuously absent in human cancer specimens, whereas X...

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PMID: 21212949
DOI: 10.1007/s00268-010-0951-0

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Expression and Function of a Large Non‐coding RNA Gene XIST in Human CancerPMID 21212949Read ↗

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