Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Misbehaviour of XIST RNA in breast cancer cells.

PloS one - 1 Jan 2009

Sirchia Silvia M, Tabano Silvia, Monti Laura, Recalcati Maria P, Gariboldi Manuela, Grati Francesca R, Porta Giovanni, Finelli Palma, Radice Paolo, Miozzo Monica

Abstract excerpt

A role of X chromosome inactivation process in the development of breast cancer have been suggested. In particular, the relationship between the breast cancer predisposing gene BRCA1 and XIST, the main mediator of X chromosome inactivation, has been intensely investigated, but still remains controversial. We investigated this topic by assessing XIST behaviour in different groups of breast carcinomas and in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to Chromosomes, Human, X

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique, Indirect

Share to In Situ Hybridization, Fluorescence

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA Interference

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Source

Open in PubMed Open full text

Identifiers

PMID: 19440381
DOI: 10.1371/journal.pone.0005559
PMCID: PMC2679222

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Misbehaviour of XIST RNA in breast cancer cells.PMID 19440381Read ↗

Loss of the Inactive X Chromosome and Replication of the Active X in BRCA1-Defective and Wild-type Breast Cancer CellsSemantic proximity Read ↗

Expression and Function of a Large Non‐coding RNA Gene XIST in Human CancerSemantic proximity Read ↗

Unleashing XIST from X-chromosome inactivationSemantic proximity Read ↗

Advances in understanding chromosome silencing by the long non-coding RNA Xist.Semantic proximity Read ↗

LncRNA Xist, X-chromosome Instability and Alzheimer's Disease.Semantic proximity Read ↗

High-resolution RNA allelotyping along the inactive X chromosome: evidence of RNA polymerase III in regulating chromatin configuration.Semantic proximity Read ↗

Role of the Xist gene in X chromosome choosing.Semantic proximity Read ↗

X-chromosome inactivation and human genetic disease.Semantic proximity Read ↗

De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation.Semantic proximity Read ↗

Chromatin structure analysis of the mouse Xist locus.Semantic proximity Read ↗

Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse.Semantic proximity Read ↗

Chromosomal silencing and localization are mediated by different domains of Xist RNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.